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J Neurochem 2011

Funding This paper was supported by San Matteo Hospital Foundation, Internal Medicine research fundings, PRIN2017. Publishers note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Translating to humans, experts cautiously estimate a 26 hour half-life when given subcutaneously

These findings suggest a strong therapeutic potential for conditions like metabolic syndrome and type 2 diabetes, where insulin resistance and excess adiposity are central pathological features